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Tramadol Drug Information
Tramadol is used to relieve moderate to moderately severe pain. It also may be used to treat pain caused by surgery and chronic conditions such as cancer or joint pain. Tramadol works by decreasing the brain\’s perception and response to pain. It also reduces the size or magnitude of the pain signal passed from one nerve to another. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.
How Taken
Tramadol comes as a tablet to take it orally. It usually is taken every 4-6 hours as needed. It may be taken with or without food. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take Tramadol exactly as directed. Tramadol can be habit-forming. Do not take a larger dose take it more often, or for a longer period than your doctor tells you to.
Warnings/Precautions
Before taking Tramadol, tell your doctor if you have kidney disease; liver disease; or a history of alcohol or drug dependence. You may not be able to take Tramadol, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above. Tramadol is in the FDA pregnancy category C. This means that it is not known whether it will be harmful to an unborn baby. Do not take this medication without first talking to your doctor if you are pregnant. It is also not known whether Tramadol passes into breast milk. Do not take Tramadol without first talking to your doctor if you are breast-feeding a baby. If you are over 75 years of age, you may be more likely to experience side effects from Tramadol. The maximum daily dose of Tramadol for people over 75 years of age is 300 mg. Tramadol is not approved by the FDA for use by children younger than 16 years of age.
Missed Dose
Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.
Possible Side Effects
Although side effects from Tramadol are not common, they can occur. The most frequently reported events were in the central nervous system (Migraine, Speech disorders) and gastrointestinal system (Gastrointestinal bleeding, Hepatitis, Stomatitis, Liver failure). Tell your doctor if any of these symptoms are severe or do not go away: dizziness, headache, drowsiness, blurred vision, upset stomach, vomiting, and diarrhea. If you experience any of the following symptoms, call your doctor immediately: fast heartbeat, redness, swelling, and itching of the face, numbness or tingling of the hands and feet, difficulty breathing, changes in urination, seizures.
Storage
Dispense in a tight container. Store at 25°C (77°F); excursions permitted to 15 - 30°C (59 - 86°F).
Overdose
Seek emergency medical attention. Symptoms of a Tramadol overdose include difficulty breathing; shallow, weak breathing; and seizures.
More Information
Do not drink alcohol while taking Tramadol. Alcohol may cause a dangerous decrease in breathing and/ or liver problems when used during treatment with Tramadol. Use caution when driving, operating machinery, or performing other hazardous activities. Tramadol may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities. Avoid sleeping pills, tranquilizers, sedatives, and antihistamines except under the supervision of your doctor. These drugs may increase drowsiness caused by Tramadol.
Disclaimer
This drug information is for your information purposes only, it is not intended that this information covers all uses, directions, drug interactions, precautions, or adverse effects of your medication. This is only general information, and should not be relied on for any purpose. It should not be construed as containing specific instructions for any particular patient. We disclaim all responsibility for the accuracy and reliability of this information, and/or any consequences arising from the use of this information, including damage or adverse consequences to persons or property, however such damages or consequences arise. No warranty, either expressed or implied, is made in regards to this information.
Does anyone know about Tramadol?
I will never consider myself an addict even if I’ve been taking Tramadol for several years. There many moments when I said to myself that I’d quit and that withdrawal was not be a dramatic experience but I just could not handle going through a rough patch. Don’t get me wrong; I know am addicted to Tramadol but I don’t have the necessary strength to identify me with the personality and feelings of an addict. The number of pills I take increases every day and frankly I do not know if there is any solution.
I started to take Tramadol 10 years ago when I was diagnosed with fibromyalgia, a rheumatic disorder generally characterized by extra-articular symptoms, with increased pain and stiffness of the muscles. After I could not get the prescription for Tramadol refilled, I went online and searched for it intensely. I could not believe it when I found it available and purchased it even if the price was quite high. I knew from the very first moment that something was not ok, that I should stop and the only person I’m hurting was I. Tramadol seemed perfect when I needed pain-relief but I also enjoyed taking it because it provoked appetite loss (I’ve always had weight problems). Silly me, I thought that Tramadol solved two problems at once; instead, it would only make me feel so much worse.
Worried so much about having a perfect figure and fighting with the disease at the same time, I lost count of how many pills of Tramadol I took in one day, sometimes taking an extra dose just in case. Well, even though I did not recognize to have an addiction, the fact that I experienced pain on the right side, I could not sleep or had a hard time breathing made me think. Maybe I had gone too far with this medication. I was not part of those taking opioids for the euphoric feeling. I never took it on such grounds. My intentions were strongly related to escaping the constant, excruciating pain and sometimes to prevent over-eating. Still, I should have realized that not the reasons were important but the consequences. I worried how I could stop it before my family found out about me taking excessive doses and feel truly ashamed of me.
Well, I stopped taking Tramadol but not because I wanted. One night, I took my usual dose of Tramadol (somewhere around 600 mg) and went to bed. My husband saw that I had fallen asleep way too fast and watched over me. The intense sweating made him to think and as he was training to become a doctor, he recognized some of the serious symptoms. My face was white, I was sweating and my pulse was weak. It was no time for searching for solutions and seeking immediate medical assistance was imperious. Arriving at the emergency ward, the doctors performed CPR on me and I was stabilized with increased difficulty. Diagnose: Tramadol overdose combined with anti-anxiety medication and anorexic drugs. Even they were amazed that I had survived. They told me without delay or hesitation that my body had suffered a lot of trauma and that it will take a long period of time before I am up and running, so to say.
Now, what do you say to a loving husband and two adorable children who are dead scared because of your actions? How do you explain that you thought taking Tramadol would make everything just fine? I was incredibly ashamed of the way I handled things and even more afraid that they will end up hating me. After all, who would want a mother that is addicted to pain killers or a wife that just can’t seem to everything right without taking a handful of pills first? But this was not the case. I have a supportive family and they all stood by my in this difficult times. United just like always, I was able to recover from my Tramadol addiction and talked with a medical specialist about what other options I have when it comes to fibromyalgia. New treatments have been discovered and I am certainly going to try them; there is nothing more incredible than knowing you can be cured and that you do not have to be dependent on opioid medicine to do that. I would never go back to the period in which I was hooked and with the help of my family and God of course, I hope I never will.
TRAMADOL - safe and effective pain medication
In the wake of growing concerns over the fatal effects of some pain relievers in the market, pain specialists continue developed recommendations for alternatives – as effective yet not as dangerous.
News on the rising deaths of patients using COX-2 inhibitors and traditional NSAIDS (Nonsteroidal Antiinflammatory Drugs) has prompted medical experts to recommend the ban or withdrawal of drugs with these ingredients from the market.
After discussing the safety data for both NSAIDs and the COX-2 inhibitors, the group endorsed an expanded role for weak opioids, which are more effective in moderate-to-severe pain than NSAIDs. At the same time these possess other significant advantages included titratability, reversibility and lack of prostaglandin-associated side effects.
The role of combinations of weak opioids and other analgesic agents - in particular, tramadol plus paracetamol - merits particular attention.
A group of international pain specialists considered that tramadol and tramadol combinations offered a useful advantage in that they were ‘NSAID-sparing’. The drug could be used in combination with lower-than-usual doses of NSAIDs. Use of tramadol is recommended by medical societies.
The panel also recommended the proper utilization of weak opioids. Side-effects, they stressed, are a common reason given for non-compliance.
The panel agreed that a policy of ‘go low, go slow’ - starting with a low dose and increasing it gradually - should be used to achieve good analgesia without intolerable side-effects.
After thorough deliberations, the group concluded that it is very important to communicate clear guidance to physicians on appropriate prescribing of analgesics in this new climate of uncertainty regarding the continuing use of COX-2 inhibitors.
Way back in 2004, there was a move for the global withdrawal of rofecoxib (Vioxx), which and concerns regarding use of other COX-2 inhibitors. Rofecoxib is used to relieve pain, tenderness and stiffness caused by arthritis. It is in a class of COX-2 exhibitors.
This then raised concerns for the need of prompt and clear guidance to physicians regarding prescription of drugs with these compositions.
NSAIDS and Cox-2
There actually are two Cox enzymes, Cox 1 and Cox-2. Both enzymes produce prostaglandins that promote inflammation, pain, and fever. However, only Cox-1 produces prostaglandins that support platelets and protect the stomach.
NSAIDs block the Cox enzymes and reduce prostaglandins throughout the body. As a consequence, ongoing inflammation, pain, and fever are reduced.
Since the prostaglandins that protect the stomach and support the platelets and blood clotting also are reduced, NSAIDs can cause ulcers in the stomach and promote bleeding.
